The URI or upper respiratory tract infection is a catch-all term used to describe the common signs and symptoms of the "common cold". Most of these infections are viral in nature and they resolve spontaneously. Occasionally, a patient will have a bacterial infection involving the sinuses or the throat, such as strep throat, or even pneumonia. These patients require antibiotic therapy. It can be difficult to differentiate the common viral infection from the more serious bacterial URI or pneumonia. If the symptoms are of new onset (<1-2 weeks) and not accompanied by fever, productive sputum, or chest pain and shortness of breath. Supportive care is likely indicated and the patient may try one of the approved over the counter preparations to relieve her symptoms. There are a variety of over the counter medications available. Anti-histamines are utilized extensively. See the list below and match the medications to the appropriate symptoms. Importantly, these medications do not "cure" the infections. They are intended to only relieve the symptoms caused by the infections.